Saturday, January 9, 2010

Medical Researchers Looking At Sandalwood

By Charity Smith

Background

Sandalwood is one of the oldest aromatic materials, being acknowledged in ancient biblical and in Indian text as well as used in religious ceremonies throughout the ages. Botanically known as a small evergreen in the genus Santalum and family Santalaceae, this modest-sized tree (up to 10 meters) provides a great deal of commerce for India and to some extent Australia and is now being examined by the medical industry for its medicinal properties. There are several species of Santalum, but only a few are used commercially, most notably Santalum album (India) and Santalum spicatum (Australia). Other tress from such places as Polynesia and Fuji are in small numbers and in great decline. Oddly, other plants such as the Bead Tree or Candlewood are known as sandalwood but are not botanically parallel. Sometimes, non-related plants such as Red Sandalwood are used as fillers for the more expensive, genuine sandalwood.

True sandalwood contains aromatic heartwood (middle) and roots which when harvested are used for furniture items as well as distilled for its highly prized essential oil. Plantations have been set aside in both India and Australia to meet growing demand for Santalum essential oil. Sandalwood harvesting and manufacturing of incense sticks, furniture and essential oil provides great employment for many in India, especially in southern India. The value of sandalwood in India cannot be overstated. Besides its ceremonial significance, sandalwood is used extensively in Indian Ayurvedic medicine. The harvest and processing of sandalwood is strictly regulated and private ownership of the trees is not permitted. Since 1792 trees have been considered of Indian royalty and thus well guarded and protected. These valued trees take decades to develop their rich aromatic wood and are not considered commercially viable until at least forty years of age, but trees have been harvested at thirty to meet rising requests for its processed products.

Much of the valuable wood is found in the roots of sandalwood and thus harvested by uprooting the entire tree versus cutting it at the trunk. In the last few years alone, the price of sandalwood has skyrocketed, mainly due to rising demand and limited supply. Increased demand has mainly come from the perfume and aromatherapy industry. Sandalwood essential oil and paste is used in Indian and Chinese medicine and of course aromatherapy botanical medicine. The perfume industry covets this oil for its ability to blend well with other perfume oils; hence, it is used extensively in hundreds of cosmetic products.

Over the centuries, the use of sandalwood and its products have been an integral part of several religious cultures. It scent, either as an essential oil or ground as incense, is thought to bring one closer to the Divine. Hindus burn incense made from sandalwood oil in burial pyres and at funerals. It's also used in temples to remind people of the heavenly realms. Yogis in India use the oil to anoint each other during ceremonies and before meditation as well deity statues often made of sandalwood itself.

Sandalwood Might be a Possible Solution to Antibiotic Resistance

In late December of 2009 a length article by the Associated Press entitled "Pressure Rises to Stop Antibiotics in Agriculture" reported on rapidly emerging bacteria that are resistant to current antibiotics from supposed misuse of antibiotics in the agriculture industry. It was all over the internet in a matter of days. The article provides quotes from professors, researchers as well as government agencies all expressing deep concern and even alarm at the rate of microbial resistance to standard treatment. The Union of Concerned Scientists (UCS) web page includes recent studies regarding antimicrobial resistance in Escherichia coli and methicillin-resistant Staphylococcus aureus (MSRA) (both of which cause great harm to humans and animals alike) linked to heavy uses in food agriculture. This scientifically sound web site also provided a press conference statement (way back in 2001) by Margaret Mellon, Ph.D., director of UCS Food and Environment Program stating that 70% of total antibiotic production is devoted to non-therapeutic uses in the cattle, swine and poultry industry. It seems plausible that over the last nine years since this press release, microbes have developed an armor of resistance to antibiotic treatments.

Concern for antibiotic-resistant microbes is worldwide. A need to find alternatives to conventional antibiotic treatment is rising. Essential oils have been gaining attention by research scientists for their antimicrobial properties. A collaborative study of researchers in Austria and Germany (Flavor and Fragrance Journal 2006 May/Jun; 21(3): 465-468) found that santalols of sandalwood (the main chemical components of sandalwood) in medium and/or high concentrations showed significant antimicrobial potential against the yeast Candida albicans, the Gram-positive bacterium Staphylococcus aureus, and the Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae.

Uses Beyond Bacterial

The Australian and Indian Santalum species, found to be similar in chemical composition, are known by aromatherapists to have such therapeutic properties as anti-inflammatory, antiphlogistic (reduces fever), antiseptic (as mentioned above), antispasmodic (relieves muscle spasms), astringent, carminative (relieves flatulence), demulcent (reduces irritation), diuretic (soft and soothing to skin), emollient, expectorant, as a sedative and general tonic. Their principle chemical constituents are alpha-santalol and beta-santalol. According to a study conducted by the Department of Pharmaceutical Sciences and South Dakota University (Anticancer Research 2007 Jul-Aug; 27(4B): 2185-8) application of the chemical compound alpha-santalol prevents UVB-induced skin tumor development in mice. Sandalwood is also thought to help alleviate the symptoms of depression as reported by the University of Maryland Medical Center (www.umm.edu).

Concluding Remarks

It is rather evident that the value of sandalwood extends across centuries and continents. It is revered by various religions, scientists, aromatherapists and perfume enthusiasts alike. What is remarkable is that uses of plants and their essential oils are bringing such world-wide engagement as their promising applications are uncovered in scientific research. A need for alternatives to conventional antibiotics as well as insecticides is clear. As less-than amiable agriculture practices surface and resistance to current antimicrobials increase, it is apparent that humankind will revert back to solutions found in nature and perhaps make a more diligent effort to conserve the very earth that sustains us.

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